Peter M Rothwell Selected Research

Antihypertensive Agents (Antihypertensives)

11/2023	Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
1/2023	The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
12/2022	Cerebral hemodynamic effects of early blood pressure lowering after TIA and stroke in patients with carotid stenosis.
10/2022	Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial.
1/2022	Long-Term Secondary Prevention: Management of Blood Pressure After a Transient Ischemic Attack or Stroke.
1/2020	A calcium channel or angiotensin converting enzyme inhibitor/angiotensin receptor blocker regime to reduced blood pressure variability in acute ischaemic stroke (CAARBS): A feasibility trial.
1/2019	Randomised controlled trial of a Calcium Channel or Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Regime to Reduce Blood Pressure Variability following Ischaemic Stroke (CAARBS): a protocol for a feasibility study.
1/2018	Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks.
6/2015	Short-term blood pressure variability in acute stroke: post hoc analysis of the controlling hypertension and hypotension immediately post stroke and continue or stop post-stroke antihypertensives collaborative study trials.
10/2014	Response of day-to-day home blood pressure variability by antihypertensive drug class after transient ischemic attack or nondisabling stroke.

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Peter M Rothwell Research Topics

Disease

140	Stroke (Strokes) 05/2024 - 01/2003
65	Ischemic Stroke 04/2024 - 10/2004
29	Transient Ischemic Attack 01/2024 - 10/2004
26	Carotid Stenosis (Carotid Artery Stenosis) 12/2022 - 07/2003
18	Pathologic Constriction (Stenosis) 12/2022 - 01/2004
14	Hypertension (High Blood Pressure) 11/2023 - 04/2005
14	Neoplasms (Cancer) 01/2018 - 10/2004
13	Hemorrhage 01/2021 - 09/2009
11	Myocardial Infarction 03/2024 - 07/2002
10	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 05/2007
8	Inflammation (Inflammations) 04/2024 - 10/2010
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 02/2012
7	Atherosclerosis 01/2024 - 10/2010
5	Atrial Fibrillation 11/2023 - 09/2010
5	Thrombosis (Thrombus) 01/2021 - 11/2010
5	Vascular Diseases (Vascular Disease) 09/2013 - 01/2008
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2024 - 08/2012
4	Lacunar Stroke 01/2023 - 01/2016
4	Leukoaraiosis 01/2023 - 09/2012
4	Cerebral Hemorrhage 10/2021 - 10/2006
4	Embolic Stroke 03/2019 - 12/2012
4	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2018 - 09/2015
3	Cognitive Dysfunction 01/2023 - 11/2014
3	Coronary Disease (Coronary Heart Disease) 01/2023 - 10/2004
3	Dementia (Dementias) 06/2020 - 11/2009
3	Diabetes Mellitus 01/2020 - 10/2014
3	Peripheral Arterial Disease 01/2019 - 09/2010
3	Neoplasm Metastasis (Metastasis) 07/2014 - 04/2012
3	Adenoma (Adenomas) 01/2013 - 05/2007
2	CADASIL 11/2023 - 01/2023
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 09/2013
2	Leukoencephalopathies 01/2020 - 07/2015
2	Cerebral Small Vessel Diseases 10/2018 - 03/2015
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2017 - 05/2014
2	Migraine Disorders (Migraine) 10/2015 - 01/2013
2	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 07/2014 - 02/2012
2	Acute Coronary Syndrome 10/2013 - 05/2010
2	Venous Thromboembolism 09/2013 - 08/2012
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 05/2012 - 01/2011
2	Infarction (Infarctions) 12/2009 - 05/2008
1	Hyperlipidemias (Hyperlipidemia) 11/2023
1	Dehydration (Water Stress) 11/2023
1	Frailty 05/2023

Drug/Important Bio-Agent (IBA)

26	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 10/2004
15	danaparoid (Orgaran)FDA Link 11/2023 - 03/2011
15	Antihypertensive Agents (Antihypertensives)IBA 11/2023 - 03/2010
10	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2013
6	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2021 - 11/2011
5	omega-Chloroacetophenone (Mace)IBA 04/2024 - 04/2016
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2024 - 10/2013
5	terutrobanIBA 03/2019 - 11/2011
5	LipidsIBA 01/2019 - 01/2005
4	Fibrinogen (Factor I)FDA Link 04/2024 - 10/2004
4	C-Reactive ProteinIBA 01/2024 - 01/2005
4	Amlodipine (Norvasc)FDA LinkGeneric 11/2023 - 05/2010
4	AnticoagulantsIBA 01/2021 - 09/2009
3	Retinaldehyde (Retinal)IBA 03/2024 - 09/2006
3	Interleukin-6 (Interleukin 6)IBA 01/2024 - 10/2014
3	Atenolol (Tenormin)FDA LinkGeneric 11/2023 - 05/2010
3	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023 - 03/2015
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2020 - 05/2010
3	Angiotensin Receptor AntagonistsIBA 01/2020 - 09/2010
3	CholesterolIBA 01/2019 - 04/2005
3	ORALIT (ORS)IBA 01/2017 - 01/2004
3	CreatinineIBA 12/2015 - 11/2014
2	Losartan (Cozaar)FDA LinkGeneric 11/2023 - 12/2015
2	4- (2- (4- hydroxybenzyl)- phenoxy)- N- methylbutylamineIBA 12/2022 - 09/2021
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 05/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2021
2	A-factor (Streptomyces)IBA 01/2022 - 10/2004
2	cyclo(Arg-Pro) (CI 4)IBA 10/2021 - 07/2002
2	Proton Pump InhibitorsIBA 01/2021 - 01/2016
2	Fibrinolytic Agents (Antithrombotic Agents)IBA 01/2021 - 01/2017
2	Calcium Channels (Calcium Channel)IBA 01/2020 - 01/2019
2	Valsartan (Vals)FDA Link 01/2020 - 01/2018
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2020 - 01/2019
2	Nitroglycerin (Dynamite)FDA LinkGeneric 11/2019 - 01/2019
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 03/2016
2	Clopidogrel (Plavix)FDA Link 01/2018 - 01/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2018 - 02/2012
2	Dipyridamole (Persantine)FDA LinkGeneric 01/2018 - 07/2016
2	Lipoproteins (Lipoprotein)IBA 01/2017 - 01/2005
2	AlbuminsIBA 12/2015 - 12/2014
2	CollagenIBA 03/2015 - 03/2010
2	DiureticsIBA 10/2014 - 05/2010
2	Lipoprotein(a)IBA 08/2012 - 01/2005
1	amlodipine-losartan drug combinationIBA 11/2023

Therapy/Procedure

35	Secondary Prevention 04/2024 - 01/2003
29	Therapeutics 05/2024 - 01/2005
21	Endarterectomy (Thromboendarterectomy) 01/2021 - 01/2004
18	Carotid Endarterectomy 01/2017 - 07/2003
8	Length of Stay 05/2023 - 10/2006
3	Institutionalization (Institutionalized Persons) 06/2020 - 10/2013
3	Stents 08/2019 - 07/2009
2	Thrombectomy 01/2024 - 06/2020
2	Contraindications 11/2015 - 06/2010
2	Chemoprevention 01/2013 - 02/2012
2	Emergency Treatment 12/2007 - 03/2005
1	Vascular Surgical Procedures 03/2024